Microcephalin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7588-50, ES7588-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010],

Alternate Name: MCPH1; Microcephalin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human MCPH1. AA range:91-140

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 93kD

Human Gene ID: 79648

Human SWISS Prot NO: Q8NEM0

Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Research Use Only