PLXNA4 Polyclonal Antibody

Catalogue Numbers: BS60789-50, BS60789-100

Sizes: 50µl, 100µl

Alternative Name: Plexin-A4; PLXNA4; KIAA1550; PLXNA4A; PLXNA4B; UNQ2820; PRO34003

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9HCM2

Host: Rabbit

Reactivity: Mouse,Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Plexin-A4, also known as PLXNA4 or FAYV2820, is a 1,894 amino acid singlepass type I membrane protein that contains one sema domain, three PSI domains and four IPT/TIG domains. Belonging to a large family of semaphorin (SEMA) receptors, plexin-A4 forms a complex with neuropilin and, once complexed, can propagate SEMA3A-induced inhibitory signals into neurons and cells, possibly playing a role in early nerve development. Four isoforms of plexin-A4 exist due to alternative splicing events. The gene encoding plexin-A4 maps to human chromosome 7, which houses over 1,000 genes and comprises
nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PLXNA4 polyclonal antibody detects endogenous levels of PLXNA4 protein.

Bioworld Molecular Weight: ~ 212 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of PLXNA4 polyclonal antibody at 1:500 dilution
Lane 1: sp2/0 whole cell lysate
Lane 2: PC12 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human PLXNA4.

Conjugate: Unconjugated

Modification: Unmodified